QOTD: What are some (GNU/|)Linux distributions that think outside the box? I’ll start.

• Bedrock Linux - A “meta distribution” that uses black magic to install packages from any distribution you can think of
  
• GoboLinux - A distribution that uses black magic to eradicate the standard filesystem hierarchy and give each package its own directory tree, e.g. /Programs/GCC/9.2.0. It’s been around for a whopping 21 years.
  

There are also the well-known ones like NixOS, Qubes, and even Gentoo but I don’t see those two mentioned very often.