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Epigenetic changes help cells adapt to low oxygen levels, study reveals
Researchers at Karolinska Institutet have discovered how cells can adjust their gene activity to survive when oxygen runs low. The study, published in Nature Cell Biology, reveals that cells use a previously unknown mechanism to control which proteins are produced—and how quickly. ⌘ Read more

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Follow-up observations by Webb confirm GRB 250702B is most energetic cosmic explosion ever recorded
Considering the immense size of the universe, it’s no surprise that space still holds plenty of secrets for us. Recently, astronomers believe they stumbled upon a kind of cosmic blast never seen before, and it’s challenging what we thought we knew about how stars die. ⌘ Read more

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Exploring the power of plants to make drugs out of sunlight
Plants are consummate chemists, using the sun’s energy and carbon dioxide from the air, to conjure a dazzling array of complex natural products in ways that cannot be replicated synthetically in the lab. ⌘ Read more

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Engineers solve the sticky-cell problem in bioreactors and other industries
To help mitigate climate change, companies are using bioreactors to grow algae and other microorganisms that are hundreds of times more efficient at absorbing CO2 than trees. Meanwhile, in the pharmaceutical industry, cell culture is used to manufacture biologic drugs and other advanced treatments, including lifesaving gene and cell therapies. ⌘ Read more

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Sniffer dogs tested in real-world scenarios reveal need for wider access to explosives
Dogs aren’t just our best friends, they’re also key allies in the fight against terrorism. Thousands of teams of explosive detection dogs and their handlers work 24/7 at airports, transit systems, cargo facilities, and public events around the globe to keep us safe. But canine detection is an art as well as a science: success depends not only on the skill of both dog and human, but also on their bond, and may vary 
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US strikes another vessel off Venezuela coast, killing six
President Trump said the vessel belonged to “narcoterrorists” and that it was “trafficking narcotics.” US officials have not provided evidence to this claim. ⌘ Read more

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US strikes another vessel off Venezuela coast, killing six
President Trump said the vessel belonged to “narcoterrorists” and that it was “trafficking narcotics.” US officials have not provided evidence to this claim. ⌘ Read more

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US strikes another vessel off Venezuela coast, killing six
President Trump said the vessel belonged to “narcoterrorists” and that it was “trafficking narcotics.” US officials have not provided evidence to this claim. ⌘ Read more

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Docker Model Runner on the new NVIDIA DGX Spark: a new paradigm for developing AI locally
We’re thrilled to bring NVIDIA DGXℱ Spark support to Docker Model Runner. The new NVIDIA DGX Spark delivers incredible performance, and Docker Model Runner makes it accessible. With Model Runner, you can easily run and iterate on larger models right on your local machine, using the same intuitive Docker experience you already trust. In this
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Chemists reveal new insights into protein linked to amyotrophic lateral sclerosis
Using advanced techniques in biophysical chemistry, a team led by Meredith Jackrel, an associate professor of chemistry, has achieved unprecedented views of a protein that may play a pivotal role in some cases of amyotrophic lateral sclerosis (ALS) and the related disorder frontotemporal dementia (FTD). Their work could open doors to new approaches for treatment and prevention. ⌘ Read more

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10 Unexpected Things Scientists Made Using DNA
Deoxyribonucleic acid, or DNA, holds the genetic information passed from parents to offspring. But researchers are driven by a bigger question—beyond inheritance, what more can you do with DNA? The results are mind-bending. From sperm plastic to woolly mammoth meatballs, here are ten projects that prove DNA is a freakishly malleable material. Related: 10 Awesome [
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The post [10 Unexpected Things Scientists Made Using DNA](https://listver 
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** Fall foliage, music, games, and text editors **
Turning to fall. While playing a little squash this morning one of the pros that hangs out at the courts asked if he could give me and one of my kids some tips. He then proceeded to spend 40 mins or so with us. It was honestly rad. Totally changed how I approach playing squash in that little time. I’m excited to play more this winter.

I’m also excited for the new The Last Dinner Party album to come out in a f 
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Satellite images reveal ancient hunting traps used by South American social groups
Satellite images have revealed an ancient system of elaborate, funnel-shaped mega traps likely built by hunters and pastoralists to catch prey in the high altitudes of northern Chile. ⌘ Read more

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US immigration enforcement using military hardware and tactics on civilians
George Chidi,  Politics and Democracy Reporter   -  The Guardian (U.K.)

_Stephan: One of the tragedies that now defines the United States, as it is seen by the rest of the world, is that Trump has created a military combat uniformed and armed for war Gestapo that is now wandering the streets of major American cities, just as the world has seen happen in other fascist control 
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Trump droht China mit 100 Prozent Zöllen
Mehrere Wochen ist es im Handelsstreit zwischen den USA und China ruhig gewesen. In der Nacht auf Samstag drohte US-PrĂ€sident Donald Trump China nun mit zusĂ€tzlichen Zöllen von 100 Prozent auf alle Importe. Als Grund nannte er, dass China angeblich ExportbeschrĂ€nkungen auf Seltenerdmetalle in Aussicht gestellt habe. ⌘ Read more

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US-Hilfe in Argentinien in der Kritik
In einem ungewöhnlichen Schritt haben die USA Argentinien am Donnerstag mit einem milliardenschweren WĂ€hrungstausch unterstĂŒtzt. Das Vorhaben lĂ€sst Zweifel an der „America First“-Politik von PrĂ€sident Donald Trump aufkommen: Kritikerinnen und Kritikern zufolge kĂ€me es neben Trumps engem VerbĂŒndeten, dem angeschlagenen ultraliberalen PrĂ€sidenten Argentiniens Javier Milei, vor allem wohlhabenden US-Investoren zugute. ⌘ Read more

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„Signal fĂŒr Anliegen der Demokratie“
Die venezolanische Oppositionspolitikerin Maria Corina Machado erhĂ€lt den Friedensnobelpreis 2025. Die Entscheidung sei ĂŒberraschend, aber verdient, so der Tenor der internationalen Reaktionen. Experten sehen auch in der BegrĂŒndung ein starkes „Signal fĂŒr das Anliegen der Demokratie“ und einen Beweis der UnabhĂ€ngigkeit des norwegischen Nobelkomitees. Kritik kam aus dem Weißen Haus. Machado widmete den Preis unterdessen auch US-PrĂ€sidenten Donald Trump. ⌘ Read more

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I noticed Google put out this article: https://android-developers.googleblog.com/2025/09/lets-talk-security-answering-your-top.html it’s very current day Google, but the comments under the YouTube video are pretty on point and I saw a few familiar faces there. There is also, unexpectedly, ways to contact Google.

First a form for “teachers, students, and hobbyists”, that I filled politely, as someone who falls under their hobbyist category. It can be filled both anonymously, or with an e-mail attached, to be contacted by them (I chose the second option).

Also a general feedback and questions form, that I was not as polite in and used to send them the following message:

I have already provided some feedback, in the teacher, student and hobbyists form/questionaire, as well as an open letter I’ve recently sent to the European Commission digital markets act team, as I do believe your proposal might not even be legal, given the fact it puts privacy-focused alternative app stores at risk (https://f-droid.org/cs/2025/09/29/google-developer-registration-decree.html) and it was proposed this early, after Google lost in court to Epic Games, over similar monopoly concerns. Why should we trust Google to be the only authority for all developer signatures, right after the European courts labeled it a gatekeeper?

Assuming this gets passed, despite justified developer backlash and at best questionable legality, can you give us any guarantees, this will not be used to target legal malware-free mods, or user privacy enhancing patchers, like the ones used for applying the ReVanced patches? I have made a few mods myself, but I am in no way associated with the ReVanced team. I just share many peoples concerns, Google Chrome has been conveniently stripped of its manifest v2 support, that made many privacy protecting extensions possible and now you’re conveniently asking for the government IDs, of all the developers, who maintain these kinds of privacy protections (be it patches, or alternative open-source apps) on Android.

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How Trump’s Supreme Court lackeys pushed us to the brink of one-man rule
Graham G. Dodds,  Professor of Political Science, Concordia University  -  Raw Story | Commentary

Stephan: This is a good assessment of how the Republicans perverted the Supreme Court, creating its corrupt fascist majority.

Image

_U.S. Supreme Court justices pose for their group port 
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RFK Jr. Ties Autism to Circumcision and Tylenol in Bonkers Rant
Farrah Tomazin ,  Political Correspondent  -  Daily Beast

_Stephan: US Secretary of Health and Human Services, Robert Kennedy, Jr, is now the man overseeing your healthcare and medical wellbeing in the Trump Republican coup. This is his latest insanity that circumcision results in autism. Never forget that Kennedy was a heroin addict in high school and college, and does not have 30 minutes of medica 
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News organizations hold out on signing Pentagon media policies ‘designed to stifle a free press’
Jeremy Barr,  Reporter  -  The Guardian (U.K.)

_Stephan: Part of the Trump Republican Party fascist strategy is to use the American military to take control of Democrat controlled cities. And one aspect of that strategy is to suppress a free press from covering the military. Here is a good description of what they are doing. It has nev 
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đŸ€” 💭 🧐 What if, What if we built our own self-hosted / small-web / community-built/run Internet on top of the Internet using Wireguard as the underlying tech? What if we ran our own Root DNS servers? What if we set a zero tolerance policy on bots, spammers and other kind of abuse that should never have existed in the first place. Hmmmm

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L’autoritĂ© et le ridicule
RĂ©cemment, Trump et son Ă©quipe on usĂ© d’une technique redoutablement efficace pour dĂ©samorcer les critiques virulentes de leurs opposants DĂ©mocrates : le ridicule. Face aux piques acerbes du reprĂ©sentant Hakeem Jeffries, leader dĂ©mocrate Ă  la Chambre des reprĂ©sentants qui dĂ©nonçait les motifs de la fermeture gouvernementale actuelle comme une pure posture partisane, les trumpistes ont ripostĂ© [
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Trump-AnklÀgerin James angeklagt
Nach der Klage gegen den frĂŒheren FBI-Chef und Widersacher von US-PrĂ€sident Donald Trump, James Comey, ist am Donnerstag auch gegen New Yorks GeneralstaatsanwĂ€ltin Letitia James Klage eingereicht worden. Sie hatte in einem Prozess erreicht, dass Trump im vergangenen Jahr wegen Betrugs zu einer dreistelligen Millionenstrafe verurteilt wurde. Nun wird ihr Bankbetrug vorgeworfen. James weist die VorwĂŒrfe zurĂŒck. ⌘ Read more

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In-reply-to » My open letter, to the European Commission digital markets act team:

@movq@www.uninformativ.de I submitted it via the form on their website (https://digital-markets-act.ec.europa.eu/contact-dma-team_en) and got the following response:

Dear citizen,

Thank you for contacting us and sharing your concerns regarding the impact of Google’s plans to introduce a developer verification process on Android. We appreciate that you have chosen to contact us, as we welcome feedback from interested parties.

As you may be aware, the Digital Markets Act (‘DMA’) obliges gatekeepers like Google to effectively allow the distribution of apps on their operating system through third party app stores or the web. At the same time, the DMA also permits Google to introduce strictly necessary and proportionate measures to ensure that third-party software apps or app stores do not endanger the integrity of the hardware or operating system or to enable end users to effectively protect security.

We have taken note of your concerns and, while we cannot comment on ongoing dialogue with gatekeepers, these considerations will form part of our assessment of the justifications for the verification process provided by Google.

Kind regards,
The DMA Team

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**Colombia’s president says boat struck by US was carrying Colombians **
The White House calls the allegation “baseless” as the US Senate rejected a measure to bar Trump from using force against the boats. ⌘ Read more

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Testing asynchronous workflows using OpenTelemetry and Istio
Learn how to test complex asynchronous workflows in cloud native applications using OpenTelemetry for context propagation and Istio for traffic routing. Explore cost-effective approaches to isolate test environments without duplicating infrastructure. Introduction Asynchronous architectures have become
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I keep getting this email occadionally:

Your iCloud storage is almost full

Now for various reasons, I don’t want my children to be using iCloud to store data, files, photos or any of the sort. They’re free to use iMessages, and other Apple services like the App Store, etc, but not storage.

So I’ve set about blocking iCloud Storage API(s) via AdGuard Home tonight as well as ensuring that my local network (client users) cannot bypass DNS policies and get out other sneaky ways, because some applications will just use other DNS servers, or DOH or DOT.

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LoRA Explained: Faster, More Efficient Fine-Tuning with Docker
Fine-tuning a language model doesn’t have to be daunting. In our previous post on fine-tuning models with Docker Offload and Unsloth, we walked through how to train small, local models efficiently using Docker’s familiar workflows. This time, we’re narrowing the focus. Instead of asking a model to be good at everything, we can specialize it:
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Where fish feed ingredients come from key for sustainability, new study finds
A new study led by researchers from the University of Tasmania, in collaboration with international partners including The University of Manchester, has found that the environmental footprint of aquaculture feeds is influenced more by where ingredients are sourced than by the types of ingredients used. ⌘ Read more

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In-reply-to » @lyse Great job!

@lyse@lyse.isobeef.org In my case it was a silver necklace, a hummingbird with a wing connected with the cold welding I mentioned using thin brass wires.

It made it in a goldsmithing class (I went to a private craftmanship high-school) so no phones allowed (no photos of it) and no “take home” of the works.

Here’s a rough sketch of it drawn by memory, the dots in the wing is where it connects to the body.

Image

The technique is basically the same as i described, but the scale is much smaller, the whole piece was about 5-6 cm on the largest side.

The rivet was made by drilling a hole through the parts, than with a short and thicker drill you widen the hole on the surface to let the rivet settle flatter on the piece, then with a rubber hammer you hit it to flatten the head until it’s snug on the hole, lock them together by doing the same on the other side.

Note that widening the hole with a thicker drill head won’t make a difference with bigger holes, mine had holes of about 1-2 mm of diameter maximum.

Here’s a sketch of what is going on for clarity.

Image

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Spontane Straßenfeiern in Gaza und Israel
Jubel, Tanz und Freudenbekundungen: Sowohl im kriegszerstörten Gazastreifen als auch in Israel ist die Erleichterung ĂŒber einen lange ersehnten Durchbruch bei den Friedensverhandlungen groß. Nach zwei Jahren Krieg stimmten Israel und die Terrororganisation Hamas der ersten Phase des Friedensplans von US-PrĂ€sident Donald Trump zu. Eine Waffenruhe soll nach dem offiziellen Beschluss des Plans durch Israels Regierung am Donnerstagabend in Kraft treten. ⌘ Read more

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